Africa Articles
Tuesday, July 7, 2026
Quaise Energy Raises $134 Million in Initial Close of Series B to Build World’s First Superhot Geothermal Power Plant
Bitget Launches Crypto Industry's First Ever US Stock Options Trading
VICTORIA, Seychelles - Friday, 03. July 2026
(GLOBE NEWSWIRE) -- Bitget, the world's largest Universal Exchange (UEX), has launched US stock options, giving users direct access to trade options on leading US-listed companies. This makes Bitget the only major crypto exchange currently offering US stock options alongside crypto and CFD markets covering gold, forex, commodities and indices.
Active features include long call and long put strategies for eligible users. Calls allow traders to take a bullish position on a stock, while puts can be used to express a bearish view or manage downside exposure. Risk for buyers is limited to the premium paid, although an option may expire without value if the expected price movement does not occur.
The launch expands Bitget's stock product line, following the introduction of tokenized stocks, its position as a leading venue for tokenized-stock trading, and pre-IPO access to private market opportunities. Stock options add another widely used Wall Street instrument to the Stock+ offering, giving active traders more ways to approach market movements, earnings cycles and portfolio risk.
Stock options expand the platform's Stock+ product, with direct-access venue for traditional US equities, built for traders familiar with established stock market products and regulated market infrastructure. The addition aligns with Bitget's wider goal of bringing crypto, stocks, commodities and other global assets into one multi-asset trading environment for users worldwide.
Demand for listed options has reached record levels. The US options market processed more than 15.2 billion contracts in 2025, an average of roughly 60 million contracts per trading day. The growth indicates wider use of options by retail and institutional participants for directional trading, hedging and capital management.
“We have consistently moved first to connect stock opportunities with our users,” said Gracy Chen, CEO at Bitget. “This has been rewarding to us and users alike. From tokenized stocks to now options, we are executing on convergence. This is innovation crypto was born to push, our products are way ahead of its time in providing advanced trading access to stocks, gold, crypto and worldwide assets.”
The initial release focuses on single-leg options buying to provide a clear entry point for users. Additional functionality, including more advanced multi-leg strategies, is planned as the Stock+ options product develops.
To mark the launch, eligible users completing their first US stock options trade may receive $15 worth of NVIDIA stock, subject to the campaign terms and regional availability.
Options trading involves significant risk and may not be suitable for all users. Product availability, supported securities and promotional rewards may vary by jurisdiction. Users should review the relevant product disclosures and understand the potential loss of the full premium before trading.
To know more about stock options trading on Bitget, visit here.
About Bitget
Bitget is the world's largest Universal Exchange (UEX), serving over 125 million users and offering access to over 2M crypto tokens, 500+ tokenized stocks, ETFs, commodities, FX, and precious metals such as gold. The ecosystem is committed to helping users trade smarter with its AI agent, which co-pilots trade execution. Bitget is driving crypto adoption through strategic partnerships such as MotoGP™. Aligned with its global impact strategy, Bitget has joined hands with UNICEF to support blockchain education for 1.1 million people by 2027. Bitget currently leads in the tokenized TradFi market, providing the industry's lowest fees and highest liquidity across 150 regions worldwide.
For more information, visit: Website | X | Telegram | LinkedIn | Discord
For media inquiries, please contact: media@bitget.com
Risk Warning: Digital asset prices are subject to fluctuation and may experience significant volatility. Investors are advised to only allocate funds they can afford to lose. The value of any investment may be impacted, and there is a possibility that financial objectives may not be met, nor the principal investment recovered. Independent financial advice should always be sought, and personal financial experience and standing carefully considered. Past performance is not a reliable indicator of future results. Bitget accepts no liability for any potential losses incurred. Nothing contained herein should be construed as financial advice. For further information, please refer to our Terms of Use.
A photo accompanying this announcement is available at https://www.globenewswire.com/NewsRoom/AttachmentNg/efe7f4d2-18e2-4216-a92c-3b3213714f28
Private Department of Sheikh Mohammed bin Khalid Al Nahyan Invests in MidOcean Energy and Forms Strategic Partnership with EIG
Monday, July 6, 2026
Orion and Shilpa Medicare Expand Partnership to Develop and Supply Nivolumab Biosimilar for Europe
(BUSINESS WIRE) -- Shilpa Medicare Limited announced that its wholly owned subsidiary, Shilpa Biologicals Private Limited, has entered into a co-development and supply agreement with Orion Corporation for intravenous (IV) nivolumab biosimilar referencing one of the world’s most widely used cancer immunotherapies to widen patient access across Europe.
Nivolumab helped usher in the era of immuno-oncology, transforming the outlook for patients with cancers such as melanoma and lung cancer. As the originator approaches loss of exclusivity in Europe, this partnership aims to put a high-quality, EU-GMP-manufactured nivolumab biosimilar within reach of more patients, reducing healthcare burden. In 2025, Nivolumab recorded sales of approximately USD4.1 billion (Source: IQVIA/IMS) Europe — underscoring the scale of the opportunity.
Under the agreement, Orion will hold the exclusive rights to register, market, distribute and sell the nivolumab biosimilar across Europe. Shilpa Biologicals will lead product development and serve as exclusive long-term commercial manufacturer and supplier for Europe. Shilpa will receive development and regulatory milestone payments, and supply revenue over life of partnership.
“Extending our partnership with Orion into immuno-oncology is a defining moment for Shilpa Biologicals,” said Vishnukant Bhutada, Managing Director, Shilpa Medicare. “It reflects the trust our partners place in our quality, our science and our ability to deliver complex biologics at scale.”
“We are pleased to add yet another product to our strategic partnership with Shilpa,” said Satu Ahomäki, EVP Generics and Consumer Health, Orion Pharma. “This agreement strengthens our operations in hospital segment in Continental Europe, and reflects progress of implementation of our division’s strategy to give everybody an access to affordable quality medicines.”
About Shilpa Medicare Limited
Shilpa Medicare, headquartered in India, is a diversified pharmaceutical and biotechnology company developing complex generics, biologics and APIs. Through Shilpa Biologicals, it operates an integrated biologics platform spanning development, scale-up and commercial manufacturing at its EU-GMP facility in Dharwad.
About Orion Corporation
Orion Pharma is a globally operating Nordic pharmaceutical company and a builder of well-being for over a hundred years. It develops, manufactures and markets human and veterinary pharmaceuticals and active pharmaceutical ingredients, with an extensive portfolio of proprietary and generic medicines and consumer health products. Its core R&D areas are oncology and pain, with proprietary products treating cancer, respiratory and neurological diseases, among others. In 2025, net sales amounted to EUR 1,890 million, with about 4,000 employees worldwide.
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Monish Shah
mediarelations@vbshilpa.com
Media Release: Financial Worries Rise and Match Health Concerns as Cost-of-Living Pressures Mount in 2026
No-Loss Trading Platform UpsideOnly Surpasses 100,000 Users Within Weeks of Launch
SAN FRANCISCO -
Rapid growth shows strong demand for a new trading model where users can make market predictions without risking their own capital
(BUSINESS WIRE) -- Perpetuals.com Ltd (Nasdaq: PDC), today announced that UpsideOnly, its risk-free trading and market prediction platform, has seen a surge in new user sign-ups, surpassing the important milestone of 100,000 traders within weeks of its launch on May 19.
UpsideOnly lets users make predictions about where global equity, commodity, forex, and crypto markets are heading without ever placing a real trade themselves. Perpetuals uses its own capital to trade on the strongest signals identified by its proprietary AI. If those trades win, Perpetuals shares the profits with the users who helped generate the signal. If the trade doesn’t make money, users lose nothing.
Reaching 100,000 users so quickly after launching is a reflection of the enormous demand for a platform that flips the traditional retail trading model on its head, with early platform data showing strong engagement across asset classes, geographies and user activity:
Users from more than 180 different countries
$38.4 billion in cumulative platform volume
1,110,385 fills across 25 instruments
US Crude Oil Futures (WTI) was the most-traded asset, ahead of Bitcoin (BTC)
These 100,000 groundbreaking users do more than trade; they generate the signals that power the business. Perpetuals's patent-pending BayesShield AI filters their collective predictions for genuine, repeatable skill, and the company trades its own capital on the strongest signals, sharing the upside with the users who produced them, a proprietary-trading model designed to monetize crowd intelligence rather than user losses.
“Reaching 100,000 users this quickly is more than a growth milestone. It is proof that the current model is broken and traders are looking for a better approach,” said Patrick Gruhn, CEO of Perpetuals. “Prediction markets have become some of the most extractive products in finance, using powerful technology to keep users engaged while most of them lose. UpsideOnly shows that the same forces – AI, market prediction and crowd intelligence – can be used in a way that rewards users instead of exploiting them.”
The unique nature of UpsideOnly means users also avoid the financial losses they would have incurred if they had been trading with their own money. To-date, UpsideOnly has saved users a total of $28.6 million in potential losses, averaging $1,429 in avoided loss per losing users. One UpsideOnly user would have lost a staggering $235,666 if trading with their own money.
About Perpetuals.com Ltd
Perpetuals.com Ltd (Nasdaq: PDC) is a fintech company developing AI-powered trading products and prediction markets, with a global footprint across the United States, Europe, and Asia. Its mission is to reduce risk through empowering retail users with intuitive, secure, and efficient trading experiences that span the world’s capital markets. UpsideOnly, the company's flagship consumer product, is the first risk-free trading platform, pairing human market insight with proprietary BayesShield AI so users can share in trading profits without ever risking their own money.
Perpetuals’s technology is used by the EU-licensed Perpetual Markets Multilateral Trading Facility (MTF), PM MTF Ltd, an affiliate of Perpetuals.com Ltd, which operates under full MiFID II, MiCA, DORA, and EMIR compliance.
We may use blog posts on our website as well as our social media accounts, including our accounts on X, LinkedIn, and Facebook, to disclose material information about the company from time to time.
Forward-Looking Statements: This press release contains forward-looking statements as defined within the meaning of the Private Securities Litigation Reform Act of 1995, including, but not limited to, statements regarding the anticipated profitability to the company and users of UpsideOnly. Words such as “expect,” “will,” “positions,” “advancing,” “projected,” “anticipated,” and other similar expressions indicate forward-looking statements, though not all forward-looking statements contain such words. These statements reflect the company’s current view with respect to future events, are subject to risks and uncertainties that could cause actual results to differ materially, including the efficacy and accuracy of BayesShield AI, regulatory scrutiny, continued user participation in the UpsideOnly platform, market conditions, the ability to realize anticipated benefits of UpsideOnly, the characterization of UpsideOnly under applicable gaming, sweepstakes, securities, and commodity-derivatives laws, patent issuance and enforceability of the BayesShield AI methodology, the company’s ability to raise capital to support the operation of the UpsideOnly platform, and risks detailed in the company’s filings with the Securities and Exchange Commission, and are necessarily based upon a number of estimates and assumptions that, while considered reasonable by the company, are inherently subject to significant business, economic, competitive, political and social uncertainties, and contingencies. Should one or more of these risks or uncertainties materialize, or should the assumptions set out by the company underlying those forward-looking statements prove incorrect, actual results may vary materially from those described herein. Individuals are cautioned that forward-looking statements are not guarantees of future performance and accordingly investors are cautioned not to put undue reliance on forward-looking statements due to the inherent uncertainty therein. These forward-looking statements are made as of the date of this press release and the company does not undertake any obligation to update these forward-looking statements, except as required by law. Perpetuals.com Ltd has an option agreement to acquire the affiliate company PM MTF Ltd, which will require a change of control approval by CySEC if exercised. Risk-free trading means that no losses from trading losses can occur to users, but does not include risks from other sources, including, but not limited to, the operational risks of the company.
View source version on businesswire.com: https://www.businesswire.com/news/home/20260706454794/en/
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Contacts
Media Contact:
press@perpetuals.com
Investor Relations:
ir@perpetuals.com
Agenus Reports Landmark BOT+BAL Data Showing 33% Three-Year Overall Survival in Refractory MSS Metastatic Colorectal Cancer Without Active Liver Metastases at ESMO GI 2026
LEXINGTON, Mass. - Monday, 06. July 2026 AETOSWire
Fully enrolled 123-patient Phase 1b cohort demonstrated 21.2-month median overall survival, 33% three-year overall survival, and a survival curve plateau beyond two years
Data presented in a heavily pretreated population where durable long-term survival is rarely reported
17% of patients alive and off all systemic anticancer therapy at last follow-up
Extended safety follow-up showed no new safety signals, no treatment-related deaths, and 98% resolution of immune-mediated diarrhea/colitis
(BUSINESS WIRE)--Agenus Inc. (Nasdaq: AGEN), a leader in immuno-oncology innovation, today announced three-year landmark Phase 1b data from the fully enrolled C-800-01 cohort evaluating botensilimab (BOT), an Fc-enhanced multifunctional anti–CTLA-4 antibody, plus balstilimab (BAL), an anti–PD-1 antibody, in patients with refractory microsatellite-stable (MSS) metastatic colorectal cancer (mCRC) without active liver metastases. The data were presented at the European Society for Medical Oncology Gastrointestinal Cancers (ESMO GI) Congress 2026 on July 2 in Munich, Germany.
BOT+BAL demonstrated clinically meaningful long-term survival in a heavily pretreated patient population with historically limited benefit from conventional immune checkpoint inhibitors and few durable treatment options after progression on standard therapies. With extended follow-up, median overall survival was 21.2 months and the three-year overall survival rate was 33%, with the Kaplan-Meier curve showing a plateau beyond two years.
Available later-line standards in refractory MSS mCRC without active liver metastases have historically reported median overall survival of approximately 10–14 months in relevant analyses, reflecting a treatment setting in which few patients have historically remained alive at later landmark timepoints and pivotal studies have generally focused on median survival rather than mature 36-month overall survival outcomes.i In this context, the survival profile, curve plateau beyond two years, and proportion of patients alive and off systemic anticancer therapy support the durability of benefit observed with BOT+BAL in this fully enrolled 123-patient Phase 1b cohort.
The data build on the two-year overall survival results presented by Dr. Benjamin L. Schlechter of Dana-Farber Cancer Institute at ESMO GI 2025 and reflect an additional year of follow-up from the same cohort. With longer follow-up, the dataset now includes 26 confirmed responses; median duration of response was not reached; and 21 patients, or 17%, were alive and off all systemic anticancer therapy at last follow-up, including 13 responders.
“These three-year data are important because they show a pattern of benefit that is not typically expected in refractory MSS colorectal cancer,” said Benjamin L. Schlechter, M.D., of Dana-Farber Cancer Institute and presenting author of the study. “These are patients who had received multiple prior lines of therapy and had few remaining options. Seeing a subset of patients remain alive and off systemic anticancer therapy after treatment speaks to the clinical relevance of these results and the potential for botensilimab plus balstilimab to change expectations for what immunotherapy may achieve in this setting.”
“BOT+BAL is not simply another checkpoint combination; it was designed to activate antitumor immunity in tumors that have been difficult to reach with conventional immunotherapy,” said Steven O’Day, M.D., Chief Medical Officer of Agenus. “With longer follow-up, we are seeing the elements that matter for a potentially differentiated immunotherapy regimen: durable survival, sustained responses, treatment-free intervals, and a manageable safety profile. These findings strengthen the foundation for BATTMAN and our broader development strategy in MSS colorectal cancer.”
The Phase 1b (NCT03860272) cohort included 123 patients with MSS mCRC without active liver metastases. Patients had received a median of three prior lines of therapy; 67% had received at least three prior lines, 15% had received prior anti–PD-(L)1 with or without anti–CTLA-4 therapy, and 30% had received at least one later-line regimen of regorafenib, trifluridine/tipiracil with or without bevacizumab, or fruquintinib.
Key Efficacy Results:
Median overall survival: 21.2 months, with 24-month and 36-month overall survival rates of 41% and 33%, respectively
Confirmed objective response rate: 21%, including three complete responses and 23 partial responses
Median duration of response: not reached; responses ranged from 1.9 months to at least 37.4 months
Disease control rate: 69% at six weeks
Clinical benefit rate: 28% at 24 weeks
Tumor regression: observed in more than 40% of patients
Treatment-free survival: 21 patients or 17%, were alive and off all systemic anticancer therapy, including 13 responders with a subset of patients remaining free from subsequent therapy or death for more than two years
In a post hoc late-line–exposed subgroup of 37 patients who had received at least one prior regimen of regorafenib, trifluridine/tipiracil with or without bevacizumab, or fruquintinib, BOT+BAL showed a confirmed objective response rate of 22%, median overall survival of 16.2 months, and a three-year overall survival rate of 30%. In this subgroup, median duration of response was 16.6 months, disease control rate was 70%, and clinical benefit rate at 24 weeks was 27%.
Safety Results
With extended follow-up, no new safety signals were observed and there were no treatment-related deaths. Immune-mediated diarrhea/colitis resolved in 98% of affected patients, with a median time to resolution of 14 days from onset.
Treatment-related immune-mediated diarrhea/colitis was the most common immune-mediated adverse event (42%; grade ≥3, 15%). The selected Phase 3 regimen of BOT 1 mg/kg plus BAL demonstrated improved tolerability, with lower rates of immune-mediated diarrhea/colitis (27%; grade ≥3, 10%) than the 2 mg/kg regimen.
Together, the mature efficacy, treatment-free survival, and extended safety findings support continued evaluation of BOT+BAL in MSS mCRC and provide rationale for the ongoing randomized Phase 3 BATTMAN trial evaluating BOT+BAL in refractory MSS/proficient mismatch repair (pMMR) metastatic colorectal cancer.
Presentation Details
Abstract Title: Botensilimab + Balstilimab in Microsatellite-Stable Metastatic Colorectal Cancer Without Active Liver Metastases: Extended Follow-Up and 3-Year Survival
Presenter: Benjamin L. Schlechter, M.D.; Dana-Farber Cancer Institute, Boston, MA, USA
Final Publication Number: 91P
Congress: European Society for Medical Oncology Gastrointestinal Cancers Congress 2026
Location: ESMO GI, 2026 | Munich, Germany
Poster Availability: The poster is available on the Agenus publications page.
About the C-800-01 Study (NCT03860272)
C-800-01 is a first-in-human Phase 1b clinical trial evaluating botensilimab with or without balstilimab in patients with advanced solid tumors. The MSS mCRC without active liver metastases cohort enrolled 123 patients who received BOT 1 mg/kg or 2 mg/kg every six weeks plus BAL 3 mg/kg every two weeks. The primary endpoint was safety and tolerability. Secondary endpoints included objective response rate, duration of response, disease control rate, and progression-free survival. Exploratory endpoints included overall survival and clinical benefit rate.
About Agenus
Agenus is a leading immuno-oncology company targeting cancer with a comprehensive pipeline of immunological agents. The company was founded in 1994 with a mission to expand patient populations benefiting from cancer immunotherapy through combination approaches, using a broad repertoire of antibody therapeutics, adoptive cell therapies (through MiNK Therapeutics) and adjuvants. Agenus has robust end-to-end development capabilities, across commercial and clinical cGMP manufacturing facilities, research and discovery, and a global clinical operations footprint. Agenus is headquartered in Lexington, MA. For more information, visit www.agenusbio.com or @agenus_bio. Information that may be important to investors will be routinely posted on our website and social media channels.
About Botensilimab (BOT)
Botensilimab (BOT) is a human Fc enhanced multifunctional anti-CTLA-4 antibody designed to boost both innate and adaptive anti-tumor immune responses. Its novel design leverages mechanisms of action to extend immunotherapy benefits to “cold” tumors which generally respond poorly to standard of care or are refractory to conventional PD-1/CTLA-4 therapies and investigational therapies. Botensilimab augments immune responses across a wide range of tumor types by priming and activating T cells, downregulating intratumoral regulatory T cells, activating myeloid cells and inducing long-term memory responses.
Approximately 1,300 patients have been treated with botensilimab and/or balstilimab in phase 1 and phase 2 clinical trials. Botensilimab alone, or in combination with Agenus’ investigational PD-1 antibody, balstilimab, has shown clinical responses across nine metastatic, late-line cancers. For more information about botensilimab trials, visit www.clinicaltrials.gov.
About Balstilimab (BAL)
Balstilimab is a novel, fully human monoclonal immunoglobulin G4 (IgG4) designed to block PD-1 (programmed cell death protein 1) from interacting with its ligands PD-L1 and PD-L2. It has been evaluated in more than 900 patients to date and has demonstrated clinical activity and a favorable tolerability profile in several tumor types.
Forward-Looking Statements
This press release contains forward-looking statements that are made pursuant to the safe harbor provisions of the federal securities laws, including statements regarding its botensilimab and balstilimab programs, expected regulatory timelines and filings, and any other statements containing the words "may," "believes," "expects," "anticipates," "hopes," "intends," "plans," "forecasts," "estimates," "will," “establish,” “potential,” “superiority,” “best in class,” and similar expressions are intended to identify forward-looking statements. These forward-looking statements are subject to risks and uncertainties that could cause actual results to differ materially. These risks and uncertainties include, among others, the factors described under the Risk Factors section of our most recent Annual Report on Form 10-K for 2025, and subsequent Quarterly Reports on Form 10-Q filed with the Securities and Exchange Commission. Agenus cautions investors not to place considerable reliance on the forward-looking statements contained in this release. These statements speak only as of the date of this press release, and Agenus undertakes no obligation to update or revise the statements, other than to the extent required by law. All forward-looking statements are expressly qualified in their entirety by this cautionary statement.
References
i Available later-line standards include regorafenib, trifluridine/tipiracil with or without bevacizumab, and fruquintinib in refractory metastatic colorectal cancer, including analyses in patients without active liver metastases (Ref 1-3).
1. Garcia-Carbonero R, et al. Presented at ESMO 2024. Poster #520P;
2. Tabernero J, et al. Presented at ASCO 2024. Poster #3584;
3. Cohen R, et al. Eur J Cancer. 2024;207:114160.
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Investors
917-362-1370 | investor@agenusbio.com
Media
781-674-4422 | communications@agenusbio.com